CD31 Antibody from ANTIBODIES-ONLINE GmbH
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|---|---|
| Antigenic Specificity | CD31 |
| Clone | MEC7-46 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | fluorescein (FITC) conjugate |
| Size | 100 µg |
| Concentration | n/a |
| Applications | Flow Cytometry, Immunofluorescence, Immunoprecipitation |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The monoclonal antibody MEC7.46 recognizes the mouse form of the platelet-endothelial cell adhesion molecule (PECAM)-1 (CD31). PECAM-1 is a member of the immunoglobulin superfamily. This heavily glycosylated protein is found in the entire vascular endothelium of adult mice and functions in mediating cellular adhesion by heterophilic and homophilic mechanisms. PECAM-1 is detected within the lymphopoietic islands in the spleen of newborn (day 12) and in the bone marrow of adult mice. Capillary endothelial cells of adult mice also express PECAM-1. The reactivity of the monoclonal antibody MEC7.46 is restricted to the isoform of the molecule that is selectively expressed by endothelial cells. The antibody precipitates a 130 kDa molecule present on the membrane of endothelial cells of all mouse blood vessels both in normal, inflamed and tumor tissues. The antigen is predominantly present at the lateral borders of endothelial cells as described for human PECAM-1. Staining of MEC7.46 can be seen on capillaries, veins, arteries and liver sinusoids. Aliases CD31, platelet-endothelial cell adhesion molecule-1 Immunogen Mouse t.end.1 cells (polyoma middle T (PmT)-transformed EC) Target Information: The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. [provided by RefSeq, May 2010]. |
| Immunogen | n/a |
| Other Names | CD31|CD31EndoCAM|GPIIA'|PECA1|PECAM-1|endoCAM|CD31 antigen|platelet endothelial cell adhesion molecule|platelet and endothelial cell adhesion molecule 1|PECAM1|Platelet/endothelial Cell Adhesion Molecule|platelet/endothelial cell adhesion molecule 1|C85791|Pecam|PECAM-1CD31|plateletendothelial cell adhesion molecule (CD31 antigen)|type I transmembrane endothelial adhesion molecule|platelet endothelial cell adhesion molecule-1|platelet and endothelial cell adhesion molecule 1 L homeolog|plateletendothelial cell adhesion molecule 1 L homeolog|pecam1.L |
| Gene, Accession # | Gene ID: 18613 |
| Catalog # | ABIN2191754 |
| Price | $608 |
| Order / More Info | CD31 Antibody from ANTIBODIES-ONLINE GmbH |
| Product Specific References | n/a |
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
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