TNFSF13 Antibody from ANTIBODIES-ONLINE GmbH
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| Antigenic Specificity | TNFSF13 |
| Clone | Apry-1-1 |
| Host Species | Mouse |
| Reactive Species | mouse |
| Isotype | IgG2b |
| Format | unconjugated |
| Size | 100 µg |
| Concentration | lot specific |
| Applications | ELISA, Functional Studies, Immunoprecipitation |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | APRIL is a cytokine that belongs to the TNF superfamily and binds to TACI and BCMA. It is implicated in the regulation of tumor cell growth and is involved in monocyte/macrophage-mediated immunological processes. Anti-APRIL (mouse) Monoclonal Antibody (recombinant) (Blocking) (APRY-1-1) is an antibody developed by antibody phage display technology using a human naive antibody gene library. These libraries consist of scFv (single chain fragment variable) composed of VH (variable domain of the human immunoglobulin heavy chain) and VL (variable domain of the human immunoglobulin light chain) connected by a polypeptide linker. The antibody fragments are displayed on the surface of filamentous bacteriophage (M13). This scFv was selected by affinity selection on antigen in a process termed panning. Multiple rounds of panning are performed to enrich for antigen-specific scFv-phage. Monoclonal antibodies are subsequently identified by screening after each round of selection. The selected monoclonal scFv is cloned into an appropriate vector containing a Fc portion of interest and then produced in mammalian cells to generate an IgG like scFv-Fc fusion protein. Target Information: The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified, such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010]. |
| Immunogen | Mouse APRIL (aa 98-232). |
| Other Names | APRIL|CD256|TALL-2|TALL2|TRDL-1|ZTNF2|TNF- and APOL-related leukocyte expressed ligand 2|a proliferation-inducing ligand|tumor necrosis factor ligand superfamily member 13|tumor necrosis factor-like protein ZTNF2|tumor necrosis factor-related death ligand-1|TNF superfamily member 13|TNFSF13|Tumor Necrosis Factor (Ligand) Superfamily, Member 13|2310026N09Rik|Trdl1|ANP32B|SLAN|Acidic leucine-rich nuclear phosphoprotein 32 family member B|SLAN protein|LOC494442|tnf13|tumor necrosis factor ligand superfamily member 13 isoform alpha proprotein|tumor necrosis factor (ligand) superfamily|member 13|tumor necrosis factor superfamily member 13|TNLG7B|proliferation-inducing ligand|tumor necrosis factor ligand 7B |
| Gene, Accession # | Gene ID: 69583 |
| Catalog # | ABIN1168999 |
| Price | $598 |
| Order / More Info | TNFSF13 Antibody from ANTIBODIES-ONLINE GmbH |
| Product Specific References | n/a |
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