Integrin beta 2 Antibody from ANTIBODIES-ONLINE GmbH
Search, find, compare suppliers for anti-Integrin beta 2 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Integrin beta 2 |
| Clone | WT-3 |
| Host Species | Mouse |
| Reactive Species | rat |
| Isotype | IgG1 |
| Format | biotin conjugate |
| Size | 100 µg |
| Concentration | 0.1 mg/ml |
| Applications | Flow Cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | LFA-1 (lymphocyte function associated molecule-1) is one of the leukocyte integrins. It is a heterodimer consisting of and subunits of 160-170 kDa and 95-100 kDa respectively. LFA-1 promotes non-antigen dependent adhesion of T-cells to a variety of lymphoid cells that bear its complementary receptor I-CAM-1 (1). It has a broad distribution and is found on most common lymphocytes. ABIN133277is specific for the subunit of LFA-1. This antibody also recognizes MAC-1 and p150, 95 as well as LFA-1, since they all contain the same subunit. It inhibits homeotypic aggregation of PHA blasts and blocks the binding of rat lymphocytes to purified rat ICAM-1 (1). Applications include immunoprecipitation, flow cytometric analysis and immunohistochemistry, cryostat sections, and in vivo/in vitro functional studies (1,2,3). Target Information: This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Aug 2012]. |
| Immunogen | n/a |
| Other Names | CD18|LAD|LCAMB|LFA-1|MAC-1|MF17|MFI7|cell surface adhesion glycoprotein LFA-1CR3P150|959 beta subunit precursor)|cell surface adhesion glycoproteins LFA-1CR3p150|95 subunit beta|complement receptor C3 beta-subunit|complement receptor C3 subunit beta|integrin beta chain|beta 2|integrin beta-2|leukocyte cell adhesion molecule CD18|leukocyte-associated antigens CD1811A|CD1811B|CD1811C|integrin subunit beta 2|ITGB2|Integrin beta 2|2E6|AI528527|Lfa1|Mac-1 beta|lymphocyte function associated antigen 1|macrophage antigen-1 beta|CD18 subunit|Leu-CAM receptor|integrin|beta 2 (antigen CD18 subunit (p95)|lymphocyte function-associated antigen 1|integrin B2)|integrin beta 2 subunit|CD18 leukocyte adhesion molecule|antigen CD18|integrin beta-2 chain|beta 2 (antigen CD18 (p95)|lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)|macrophage antigen 1 (mac-1) beta subunit)|itgb2-a|itgb2-b|integrin beta-2 subunit|integrin subunit beta 2 S homeolog|beta 2 (complement component 3 receptor 3 and 4 subunit)|itgb2.S |
| Gene, Accession # | Gene ID: 309684 |
| Catalog # | ABIN133277 |
| Price | $294 |
| Order / More Info | Integrin beta 2 Antibody from ANTIBODIES-ONLINE GmbH |
| Product Specific References | n/a |
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
Schloss-Rahe-Str. 15
52072 Aachen GERMANY
P: +49 (0)241 95 163 153
F: +49 (0)241 95 163 155
info@antibodies-online.com
Orders: orders@antibodies-online.com
Technical Support: support@antibodies-online.com
https://www.antibodies-online.com
Profile of ANTIBODIES-ONLINE GmbH
Return to Antibodies