PROS1 Antibody from ANTIBODIES-ONLINE GmbH
Search, find, compare suppliers for anti-PROS1 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | PROS1 |
| Clone | polyclonal |
| Host Species | Goat |
| Reactive Species | human |
| Isotype | n/a |
| Format | unconjugated |
| Size | 1 mL |
| Concentration | n/a |
| Applications | ELISA, Immunodiffusion, Immunoelectrophoresis, Radial Immunodiffusion |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Goat anti-PROS1 polyclonal antibody, unconjugated |
| Immunogen | Protein S is a vitamin K dependent plasma glycoprotein (MW 69,000) which belongs to a group of coagulation inhibitors consisting itself of proteinases. It circulates in the blood in a free active form and in an inactive form bound to C4b binding protein. Protein S is also released by thrombin stimulation from platelet alpha-granules. Protein S acts a s a cofactor for activated protein C (pCa) enhancing the cleavage of factors Va and VIIIa, producing anticoagulation by decreasing the conversion of prothrombin to thrombin. It also stimulates the fibrinolytic system. Protein S looses much of its coagulant cofactor activity after cleavage by thrombin, a process which is inhibited by thrombomodulin in the presence of free calcium ions. Plasma concentration of protein S may be significantly reduced below normal adult levels (2.5 mg/ml) in patients with hereditary deficiency of protein S or suffering a combination of deep vein thrombosis, superficial thrombophlebitis and pulmonary embolism. Substances such as bacterial endotoxins, tumour necrosis factor and immune mediator interleukin 1 also reduce the protein S level in plasma. Oral contraceptives also depress pS activity. A reduction in plasma protein S during pregnancy usually returns to normal after parturition. Freund's complete adjuvant is used in the first step of the immunization procedure. |
| Other Names | PROS|PS21|PS22|PS23|PS24|PS25|PSA|THPH5|THPH6|protein Sa|vitamin K-dependent plasma protein S|vitamin K-dependent protein S|protein S|PROS1|zgc:154001|AW214361|protein S (alpha) |
| Gene, Accession # | Gene ID: 5627 |
| Catalog # | ABIN458052 |
| Price | $492 |
| Order / More Info | PROS1 Antibody from ANTIBODIES-ONLINE GmbH |
| Product Specific References | n/a |
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
Schloss-Rahe-Str. 15
52072 Aachen GERMANY
P: +49 (0)241 95 163 153
F: +49 (0)241 95 163 155
info@antibodies-online.com
Orders: orders@antibodies-online.com
Technical Support: support@antibodies-online.com
https://www.antibodies-online.com
Profile of ANTIBODIES-ONLINE GmbH
Return to Antibodies