CD45RC Antibody from ANTIBODIES-ONLINE GmbH
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| Antigenic Specificity | CD45RC |
| Clone | OX-22 |
| Host Species | Mouse |
| Reactive Species | rat |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 250 µg |
| Concentration | 1.0 mg/ml |
| Applications | Flow Cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rat Leukocyte Common Antigen has been shown to exist in different forms on different lymphoid cell types. Rat L-CA on thymocytes gives one main band at 180 kDa, T cells show 4 bands at 180, 190, 200 and 220 kDa and B cells one broad band at 240 kDa. T helper and T cytotoxic cell subsets show the same 4 bands with some differences in the proportions of each. ABIN133289reacts with the high molecular weight form of the leukocyte common antigen (2) which includes the 240 kDa form on B cells as well as a subfraction of the 190, 200 and 220 kDa forms, but not with the 180 kDa form of T cells or thymocytes. (5) Thus, ABIN133289reacts with B cells, cytotoxic T cells and helper cells for T cell responses but not with thymocytes or helper T cells for in vivo antibody responses. (5) Consequently, this antibody can be used to identify B cells, all CD8 ve T cells, 75% CD4 ve T cells and 50% bone marrow cells. This, antibody also divides rat CD4 ve T cells into two phenotypically distinct populations differing in their helper activities (6,7). Target Information: member of a family of heavily glycosylated leukocyte cell surface glycoproteins, displays extensive O-glycosylation [RGD, Feb 2006]. |
| Immunogen | Phytohaemagglutinin-activated rat lymph node cells . FUSION PARTNER: P3-NSI-1-Ag4 (NS1/1) . IMMUNOCYTE DONOR: BALB/c Spleen |
| Other Names | B220|CD45|CD45R|GP180|L-CA|LCA|LY5|T200|CD45 antigen|T200 glycoprotein|T200 leukocyte common antigen|protein tyrosine phosphatase|receptor type|c polypeptide|receptor-type tyrosine-protein phosphatase C|protein tyrosine phosphatase, receptor type C|PTPRC|CD45RC|RT7|receptor-type|leucocyte common antigen|leukocyte common antigen A|leukocyte common antigen B|protein tyrosine phosphatase, receptor type, C |
| Gene, Accession # | Gene ID: 24699 |
| Catalog # | ABIN133289 |
| Price | $288 |
| Order / More Info | CD45RC Antibody from ANTIBODIES-ONLINE GmbH |
| Product Specific References | n/a |
ANTIBODIES-ONLINE GmbH
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