Edit |   |
---|---|
Antigenic Specificity | APOE |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human, rat |
Isotype | n/a |
Format | unconjugated |
Size | 500 µg |
Concentration | 1.0 mg/mL |
Applications | ELISA, Immunohistochemistry, Immunoprecipitation, Western Blotting |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: Anti Apolipoprotein E Antibody recognizes the gene product of APOE. Apolipoprotein E is found in the chylomicron and IDLs that binds to a specific receptor on liver cells and peripheral cells. Apolipoprotein E is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This antibody is suitable for cardiovascular research. Gene Name: APOE Target Information: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jul 2008]. |
Immunogen | Immunogen: Apolipoprotein Type E was isolated from human plasma by density gradient centrifugation followed by HPLC purification. Immunogen Type: Native Protein |
Other Names | AD2|LDLCQ5|LPG|apo-E|apolipoprotein E3|apolipoprotein E|APOE|AI255918|APOEA|apoprotein|im:7036787|wu:fb69a05|zgc:110064|ApoE-1|apolipoprotein Ea|cb82|fa96d02|hm:zeh1311|wu:fa03d06|wu:fa96d02|wu:fa97a11|wu:fc95h12|wu:fj54e06|ApoE-2|apo-Eb|zeh1311|apolipoprotein Eb|apoeb |
Gene, Accession # | Gene ID: 348, 25728 |
Catalog # | ABIN5596681 |
Price | $614 |
Order / More Info | APOE Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |