Edit |   |
---|---|
Antigenic Specificity | Ki-67 |
Clone | Ki-67 |
Host Species | Mouse |
Reactive Species | cow, human |
Isotype | IgG1 |
Format | phycoerythrin (PE) conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blotting |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Ki-67 is a highly protease-sensitive nuclear protein expressed in two isoforms (345 kDa and 395 kDa), both of which are identified by the antibody clone Ki-67. The Ki-67 antigen is essential for cell proliferation and its expression is restricted to the cycling cells. It is detected in G1, S, G2 and M phase, whereas it is absent in cells which are in G0 phase and it is not associated with DNA repair processes. Ki-67 thus represents an important tool for detection of proliferating cells, which is of great importance in tumor diagnostics and is commonly used as a prognostic factor in cancer studies. Target Information: This gene encodes a nuclear protein that is associated with and may be necessary for cellular proliferation. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X. [provided by RefSeq, Mar 2009]. |
Immunogen | Nuclei of the Hodgkin lymphoma cell line L428 |
Other Names | KIA|MIB-1|antigen KI-67|proliferation-related Ki-67 antigen|marker of proliferation Ki-67|MKI67|Antigen Identified By Monoclonal Antibody Ki-67|Ki-67|D630048A14Rik|Ki67|antigen identified by monoclonal antibody Ki 67|nucleolar protein interacting with the FHA domain of MKI67|NIFK|marker of proliferation Ki-67 L homeolog|mki67.L|MGC132156|marker of proliferation Ki-67 S homeolog|mki67.S|antigen KI-67-like |
Gene, Accession # | Gene ID: 4288, 513220 |
Catalog # | ABIN2749194 |
Price | $484 |
Order / More Info | Ki-67 Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |