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Antigenic Specificity | RNF34 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 500 µg |
Concentration | 5.0 mg/mL |
Applications | ELISA, Western Blotting |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. RNF34, also known as RING finger protein 34, RING finger protein RIFF, FYVE-RING finger protein Momo, Human RING finger homologous to inhibitor of apoptosis protein, hRFI, Caspases-8 and -10-associated RING finger protein 1, CARP-1 and Caspase regulator CARP1, is a novel modulator of NF-kB activation. RNF34 possesses E3 ubiquitin protein ligase activity and has been shown to regulate the levels ofTarget Information: The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2012]. |
Immunogen | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to amino acids 1-373 of human RNF34 protein. Immunogentype:Recombinant |
Other Names | CARP-1|CARP1|RFI|RIF|RIFF|hRFI|E3 ubiquitin-protein ligase RNF34|FYVE-RING finger protein MOMO|RING finger protein RIFF|caspase regulator CARP1|caspases-8 and -10-associated RING finger protein 1|human RING finger homologous to inhibitor of apoptosis protein|ring finger protein 34|RNF34|AW061037|AW536122|BC004042|C88279|phafin 1|phafin-1|Momo|RING finger protein MOMO|fi35g06|wu:fi35g06|zgc:114043|ring finger protein 34a|rnf34a|Residual feed intake |
Gene, Accession # | Gene ID: 80196 |
Catalog # | ABIN129536 |
Price | $592 |
Order / More Info | RNF34 Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |