Myosin 9 Antibody from ANTIBODIES-ONLINE GmbH
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| Antigenic Specificity | Myosin 9 |
| Clone | SF9 |
| Host Species | Human |
| Reactive Species | Drosophila melanogaster, human, mouse, rat |
| Isotype | IgG2 |
| Format | Atto 488 conjugate |
| Size | 100 µg |
| Concentration | lot specific |
| Applications | Immunocytochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | anti-Myosin IIA (non-muscle), monoclonal antibody (recombinant) (SF9) is an antibody developed by antibody phage display technology using a human naive antibody gene library. These libraries consist of scFv (single chain fragment variable) composed of VH (variable domain of the human immunoglobulin heavy chain) and VL (variable domain of the human immunoglobulin light chain) connected by a polypeptide linker. The antibody fragments are displayed on the surface of filamentous bacteriophage (M13). This scFv was selected by affinity selection on antigen in a process termed panning. Multiple rounds of panning are performed to enrich for antigen-specific scFv-phage. Monoclonal antibodies are subsequently identified by screening after each round of selection. The selected monoclonal scFv is cloned into an appropriate vector containing a Fc portion of interest and then produced in mammalian cells to generate an IgG like scFv-Fc fusion protein. Target Information: This gene encodes a conventional non-muscle myosin, this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness. [provided by RefSeq, Dec 2011]. |
| Immunogen | Full length myosin IIA from rat liver. |
| Other Names | BDPLT6|DFNA17|EPSTS|FTNS|MHA|NMHC-II-A|NMMHC-IIA|NMMHCA|cellular myosin heavy chain|type A|myosin heavy chain 9|myosin heavy chain|non-muscle IIa|myosin-9|non-muscle myosin heavy chain A|non-muscle myosin heavy chain IIa|non-muscle myosin heavy polypeptide 9|nonmuscle myosin heavy chain II-A|MYH9|Myosin 9|C80049|D0Jmb2|E030044M24Rik|Fltn|Myhn-1|Myhn1|NMHC II-A|NMHCIIA|NMMHC II-a|NMMHC-A|TU72.6|flectin|myosin IIA|myosin heavy chain IX|myosin, heavy polypeptide 9, non-muscle|fi22c04|myh9l2|wu:fi22c04|wu:fj85e11|zgc:162029|zgc:66164|fj85e11|myosin|heavy chain 9|non-muscle|like-2|heavy polypeptide 9|zNMHC-IIA|myosin, heavy chain 9a, non-muscle|myh9a|NMMHC|nonmuscle|myosin, heavy chain 9, non-muscle|KLGPTK7|nonmuscle myosin II heavy chain A|myosin, heavy chain 9, non-muscle L homeolog|myh9.L |
| Gene, Accession # | Gene ID: 4627, 17886, 100911597 |
| Catalog # | ABIN5564289 |
| Price | $637 |
| Order / More Info | Myosin 9 Antibody from ANTIBODIES-ONLINE GmbH |
| Product Specific References | n/a |
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