KappaB Ras Antibody from ANTIBODIES-ONLINE GmbH

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Antigenic SpecificityKappaB Ras
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatunconjugated
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA, Immunohistochemistry (Paraffin-embedded Sections), Western Blotting
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DescriptionKappaB ras Antibody: KappaB ras-1 (κ,B-ras-1) and kappaB-ras-2 are two small proteins that similar to Ras-like small GTPases that associate with Iκ,B (Iκ,B), an inhibitor of the transcription factor NF-κ,B. Iκ,B exists in two homologous forms, Iκ,B-alpha and Iκ,B-beta, although Iκ,B-beta contains a unique 47-amino acid region within its ankyrin domain. While inactive Iκ,B-alpha-NF-κ,B complexes can shuttle in and out of the nucleus, Iκ,B-beta-NF-κ,B complexes are retained exclusively in the cytoplasm. It is suggested that kappaB-ras proteins preferentially bind to the Iκ,B-beta form through this unique insert within the ankyrin region, thus modulating the cellular location of Iκ,B-beta and regulating the rate of degradation of Iκ,B-beta. This antibody detects both kappaB-ras1 and kappaB-ras2.
ImmunogenKappaB ras antibody was raised against a 18 amino acid synthetic peptide from near the center of human KappaB ras 1. The immunogen is located within amino acids 80 - 130 of KappaB ras.
Other Namesn/a
Gene, Accession #n/a
Catalog #ABIN6990380
Price$519
Order / More InfoKappaB Ras Antibody from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
Schloss-Rahe-Str. 15
52072 Aachen GERMANY
P: +49 (0)241 95 163 153
F: +49 (0)241 95 163 155

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