CD45RC Antibody from ANTIBODIES-ONLINE GmbH
Search, find, compare suppliers for anti-CD45RC antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | CD45RC |
| Clone | RP1-12 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | fluorescein (FITC) conjugate |
| Size | 100 tests |
| Concentration | n/a |
| Applications | Flow Cytometry, Immunofluorescence |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody reacts with CD45RC on pre-B lymphocytes,B cells,CD8 T suppressor/cytotoxic cells,and a subset of CD4 T helper (Th)lymphocytes. It weakly reacts with thymocytes.4 CD45RC is a high-molecular-weight isoform of CD45 (Leukocyte Common Antigen),its level of expression distinguishes subpopulations of CD4 T cells with Th1-like and Th2-like effector functions. Levels of expression of CD45RC have also been reported to distinguish resting from activated T cells at various stages of maturation. CD45 is a member of the Protein Tyrosine Phosphatase (PTP) family: Its intracellular (COOH-terminal)region contains two PTP catalytic domains,and the extracellular region is highly variable due to alternative splicing of exons 4,5,and 6 (designated A,B,and C,respectively),plus differing levels of glycosylation. The CD45 isoforms detected in the rat are cell type-,maturation-,and activation state-specific. The CD45 isoforms play complex roles in T-cell and B-cell antigen receptor signal transduction. Target Information: member of a family of heavily glycosylated leukocyte cell surface glycoproteins, displays extensive O-glycosylation [RGD, Feb 2006]. |
| Immunogen | n/a |
| Other Names | B220|CD45|CD45R|GP180|L-CA|LCA|LY5|T200|CD45 antigen|T200 glycoprotein|T200 leukocyte common antigen|protein tyrosine phosphatase|receptor type|c polypeptide|receptor-type tyrosine-protein phosphatase C|protein tyrosine phosphatase, receptor type C|PTPRC|CD45RC|RT7|receptor-type|leucocyte common antigen|leukocyte common antigen A|leukocyte common antigen B|protein tyrosine phosphatase, receptor type, C |
| Gene, Accession # | Gene ID: 5788 |
| Catalog # | ABIN1112166 |
| Price | $334 |
| Order / More Info | CD45RC Antibody from ANTIBODIES-ONLINE GmbH |
| Product Specific References | n/a |
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
Schloss-Rahe-Str. 15
52072 Aachen GERMANY
P: +49 (0)241 95 163 153
F: +49 (0)241 95 163 155
info@antibodies-online.com
Orders: orders@antibodies-online.com
Technical Support: support@antibodies-online.com
https://www.antibodies-online.com
Profile of ANTIBODIES-ONLINE GmbH