C3 Antibody from ANTIBODIES-ONLINE GmbH

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Antigenic SpecificityC3
Clone2B10B9B2
Host SpeciesMouse
Reactive Speciesrat
Isotypen/a
Formatunconjugated
Size100 µg
Concentrationn/a
ApplicationsImmunoassay, Western Blotting
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DescriptionThe monoclonal antibody 2B10B9B2 reacts with an epitope on C3b. The antibody reacts both with intact C3 and C3b. The complement factor C3 consists of an alpha- and a beta-chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical and mannose binding lectin activation pathways lead to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to formation of the alpha- chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues including renal epithelial cells and hepatocytes. Target Information: Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptible to bacterial infection. [provided by RefSeq, Feb 2009].
Immunogenn/a
Other NamesAHUS5|ARMD9|ASP|C3a|C3b|CPAMD1|C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1|C3a anaphylatoxin|acylation-stimulating protein cleavage product|complement C3|complement component C3|complement component C3a|complement component C3b|prepro-C3|C3|Complement Component 3|AI255234|HSE-MSF|Plp|acylation stimulating protein|complement component 3d|complement factor 3|C3-1|sb:cb26|si:dkey-76b14.4|wu:fi34b03|wu:fj86e11|cb26|complement component c3a, duplicate 1|c3a.1|C3d|complement C3 alpha chain|complement component 3 L homeolog|c3.L|complement component C3d|LOC443475|complement C3-like|LOC100060539
Gene, Accession #Gene ID: 24232
Catalog #ABIN2192120
Price$683
Order / More InfoC3 Antibody from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
Schloss-Rahe-Str. 15
52072 Aachen GERMANY
P: +49 (0)241 95 163 153
F: +49 (0)241 95 163 155

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