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Antigenic Specificity | C3 |
Clone | 2B10B9B2 |
Host Species | Mouse |
Reactive Species | rat |
Isotype | n/a |
Format | unconjugated |
Size | 100 µg |
Concentration | n/a |
Applications | Immunoassay, Western Blotting |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The monoclonal antibody 2B10B9B2 reacts with an epitope on C3b. The antibody reacts both with intact C3 and C3b. The complement factor C3 consists of an alpha- and a beta-chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical and mannose binding lectin activation pathways lead to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to formation of the alpha- chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues including renal epithelial cells and hepatocytes. Target Information: Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptible to bacterial infection. [provided by RefSeq, Feb 2009]. |
Immunogen | n/a |
Other Names | AHUS5|ARMD9|ASP|C3a|C3b|CPAMD1|C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1|C3a anaphylatoxin|acylation-stimulating protein cleavage product|complement C3|complement component C3|complement component C3a|complement component C3b|prepro-C3|C3|Complement Component 3|AI255234|HSE-MSF|Plp|acylation stimulating protein|complement component 3d|complement factor 3|C3-1|sb:cb26|si:dkey-76b14.4|wu:fi34b03|wu:fj86e11|cb26|complement component c3a, duplicate 1|c3a.1|C3d|complement C3 alpha chain|complement component 3 L homeolog|c3.L|complement component C3d|LOC443475|complement C3-like|LOC100060539 |
Gene, Accession # | Gene ID: 24232 |
Catalog # | ABIN2192120 |
Price | $683 |
Order / More Info | C3 Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |