TRKCT1 Antibody from ANTIBODIES-ONLINE GmbH

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Antigenic SpecificityTRKCT1
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse
Isotypen/a
Formatunconjugated
Size100 µg
Concentration1.53 mg/mL
ApplicationsELISA, Western Blotting
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DescriptionThis antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. TrkCT1, also named neurotrophic tyrosine kinase receptor type 3 (Ntrk3) non-catalytic isoform 2, is a non-catalytic isoform of TrkC, the high affinity receptor for Neurotrophin-3 (NT-3). This isoform lacks the kinase domain that is responsible for signaling by the full-length isoform. TrkCT1 is the product of an alternative splicing of Ntrk3 that leaves the extracellular and transmembrane domains intact but includes a shorter intracellular domain encoded by exons 13b and 14b. Recent studies indicate that the short cytoplasmic tail binds the scaffold protein Tamalin in a ligand-dependent manner and further activates the Arf6-Rac1 signaling pathway (Esteban et al., 2006).
ImmunogenThis affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids near the of mouse TrkCT1 protein.
Other Namesn/a
Gene, Accession #n/a
Catalog #ABIN233824
Price$537
Order / More InfoTRKCT1 Antibody from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
Schloss-Rahe-Str. 15
52072 Aachen GERMANY
P: +49 (0)241 95 163 153
F: +49 (0)241 95 163 155

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