Edit |   |
---|---|
Antigenic Specificity | TNF alpha |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry, Immunoassay, Immunostaining, Neutralization, Western Blotting |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody reacts with human natural and recombinant TNF-alpha as assessed by ELISA. The antibody inhibits the biological activity of human natural and recombinant TNF-alpha as determined with L929 and WEHI cells in a cytotoxicity assay. The antibody cross reacts with rhesus and cynomolgus natural TNF- alpha and lacks cross reactivity with human lymphotoxin. Target Information: This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008]. |
Immunogen | n/a |
Other Names | DIF|TNF-alpha|TNFA|TNFSF2|APC1 protein|TNF|macrophage-derived|monocyte-derived|TNF-a|cachectin|tumor necrosis factor ligand superfamily member 2|tumor necrosis factor-alpha|tumor necrosis factor|Tumor Necrosis Factor alpha|TNF alpha|RATTNF|tumor necrosis factor (TNF superfamily|member 2)|TNFalpha|Tnfsf1a|tumor-necrosis factor|cTNF|tumour necrosis factor|tnfa-like|TNF2|lta|tumor necrosis factor b (TNF superfamily, member 2)|tnfb|ATP-binding cassette|sub-family F (GCN20)|member 1|xtnf|tumour necrosis factor alpha|alpha|LOC103694380|TNF-alpha 1|TNF1|tumor necrosis factor a (TNF superfamily, member 2) |
Gene, Accession # | Gene ID: 7124 |
Catalog # | ABIN2192175 |
Price | $683 |
Order / More Info | TNF alpha Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |