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Antigenic Specificity | L-Selectin |
Clone | DREG56 |
Host Species | Mouse |
Reactive Species | baboon, human |
Isotype | IgG1 kappa |
Format | fluorescein (FITC) conjugate |
Size | 25 tests |
Concentration | 25 µg/mL |
Applications | Flow Cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody reacts with a 76-95 kDa glycoprotein referred to as L-selectin (CD62L, LECAM, LAM-1, Leu8). As a human lymphocyte homing receptor for peripheral lymph node high endothelial venules (HEV), CD62L is expressed on neutrophils, monocytes, T- and B-lymphocyte subsets and NK cells. Target Information: This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]. |
Immunogen | PMA-activated human peripheral blood leukocytes |
Other Names | CD62L|LAM1|LECAM1|LEU8|LNHR|LSEL|LYAM1|PLNHR|TQ1|CD62 antigen-like family member L|L-selectin|gp90-MEL|leukocyte surface antigen Leu-8|leukocyte-endothelial cell adhesion molecule 1|lymph node homing receptor|lymphocyte adhesion molecule 1|pln homing receptor|selectin L|SELL|AI528707|LECAM-1|Ly-22|Ly-m22|Lyam-1|LAM-1|leukocyte adhesion molecule 1|lymphocyte antigen 22|lymphocyte surface MEL-14 antigen|selectin, lymphocyte|A.11|selectin|lymphocyte|selectin L (lymphocyte adhesion molecule 1)|SELE|selectin E (endothelial adhesion molecule 1) |
Gene, Accession # | Gene ID: 6402 |
Catalog # | ABIN2704309 |
Price | $147 |
Order / More Info | L-Selectin Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |