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Antigenic Specificity | PA2G4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 120 µL |
Concentration | 0.84 mg/mL |
Applications | ELISA, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PA2G4 (EBP1),first identified as an ErbB3 binding protein,is a 38 kDa protein that is widely expressed in cultured cells and tissues. The presence of several functional domains such as a nuclear localization sequence (NLS),LxxLL and LxCxE suggests the involvement of Ebp1 in cell signaling pathways and gene transcription regulation. This antibody is a mouse mono-clonal antibody raised against full length PA2G4 of human origin. Target Information: This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified. [provided by RefSeq, Jul 2008]. |
Immunogen | Fusion protein of human PA2G4 |
Other Names | EBP1|HG4-1|p38-2G4|ErbB-3 binding protein 1|ErbB3-binding protein Ebp1|cell cycle protein p38-2G4 homolog|erbB3-binding protein 1|proliferation-associated protein 2G4|proliferation-associated 2G4|PA2G4|Proliferation-Associated 2G4, 38kDa|38kDa|si:dz150i12.2|wu:fb19b11|wu:ft56d05|zgc:86732|proliferation-associated 2G4, a|pa2g4a|pa2g4-a|proliferation-associated 2G4 L homeolog|pa2g4.L|DKFZp469G2132|proliferation-associated protein 2G4-like|LOC100519773|MGC81621|similar to proliferation-associated 2G4|38kD|proliferation-associated 2G4 S homeolog|pa2g4.S|proliferation-associated protein 2G4 pseudogene|LOC693641|AA672939|Plfap|IRES-specific cellular trans-acting factor 45 kDa|ITAF45|mpp1|proliferation-associated protein 1|protein p38-2G4 |
Gene, Accession # | Gene ID: 5036, 18813, 288778 |
Catalog # | ABIN7247851 |
Price | $319 |
Order / More Info | PA2G4 Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |