NEDD1 Antibody from ANTIBODIES-ONLINE GmbH
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| Antigenic Specificity | NEDD1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | unconjugated |
| Size | 100 µL |
| Concentration | 40 mg/mL |
| Applications | ELISA, Western Blotting |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. Microtubules are polymers of tubulin, which exist as heterodimers of alpha-tubulin and beta-tubulin. NEDD1 (neural precursor expressed, developmentally down-regulated protein1, also called GCP-WD) is a centrosomal protein that in mammals associates with the gamma-tubulin ring complex (γ-TuRC). γ-TuRC is critical for initiation, or nucleation, of the microtubule assembly. In association with this complex, NEDD1 plays an important role in targeting the γ-TuRC complex to the site of microtubule nucleation and to the mitotic spindle. These events are essential for proper bipolar spindle formation and mitotic progression. Given the casual link between improper spindle function and tumorigenesis, characterization of Nedd1 function will be important to better understand various mechanisms underlying mitotic regulation, chromosome segregation, and cancer development.Target Information: Required for mitosis progression. Promotes the nucleation of microtubules from the spindle (By similarity). May play an important role during the embryonic development and differentiation of the central nervous system. |
| Immunogen | Anti-NEDD1 was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to the 343-667 region of human Nedd1. Immunogen Type: RecombinantProtein |
| Other Names | GCP-WD|TUBGCP7|NEDD-1|neural precursor cell expressed developmentally down-regulated protein 1|protein NEDD1|neural precursor cell expressed, developmentally down-regulated 1|NEDD1|neural precursor cell expressed|developmentally down-regulated gene 1|MGC81767|developmentally down-regulated 1|neural precursor cell expressed, developmentally down-regulated 1 L homeolog|nedd1.L|MGC145237|cilia and flagella associated protein 54|CFAP54|neural precursor cell expressed, developmentally down-regulated gene 1|fb78g03|wu:fb78g03|zgc:63491 |
| Gene, Accession # | Gene ID: 121441 |
| Catalog # | ABIN964675 |
| Price | $537 |
| Order / More Info | NEDD1 Antibody from ANTIBODIES-ONLINE GmbH |
| Product Specific References | n/a |
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
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