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Antigenic Specificity | CD44 |
Clone | polyclonal |
Host Species | Rat |
Reactive Species | mouse |
Isotype | n/a |
Format | fluorescein (FITC) conjugate |
Size | 100 µg |
Concentration | 0.1 mg/ml |
Applications | ELISA, Flow Cytometry, Immunohistochemistry, Immunoprecipitation |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | anti-mouse CD44 monoclonal antibody reacts with all isoforms of CD44 (Pgp-1, Ly-24) a polymorphic glycoprotein which is broadly distributed on hematopoietic cells and a variety of nonhematopoietic cells 1,2. CD44 is a cell adhesion receptor and its primary ligand is hyaluronan This antibody is suitable for use in flow cytometry. It has also been reported to have application for immunoprecipitation, detection of soluable CD44 with ELISA, IHC of frozen sections and paraffin sections, and complement depletion 1,2,3 Target Information: The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]. |
Immunogen | n/a |
Other Names | CDW44|CSPG8|ECMR-III|HCELL|HUTCH-I|IN|LHR|MC56|MDU2|MDU3|MIC4|Pgp1|CD44 antigen|GP90 lymphocyte homingadhesion receptor|Hermes antigen|cell surface glycoprotein CD44|chondroitin sulfate proteoglycan 8|epican|extracellular matrix receptor III|hematopoietic cell E- and L-selectin ligand|heparan sulfate proteoglycan|homing function and Indian blood group system|hyaluronate receptor|phagocytic glycoprotein 1|CD44 molecule (Indian blood group)|CD44|syndecan 4 (amphiglycan|ryudocan)|syndecan-4|syndecan 4|SDC4|AU023126|AW121933|AW146109|HERMES|Ly-24|Pgp-1|PGP-I|lymphocyte antigen 24|phagocytic glycoprotein I|CD44A|METAA|RHAMM|Cell surface glycoprotein CD44 (hyaluronate binding protein)|CD44-like protein|extracellular matrix receptor-III|lymphocyte surface antigen precursor CD44|XCD44|mutch-i|CD44 molecule (Indian blood group) S homeolog|hyaluronan receptor CD44|cd44.S |
Gene, Accession # | Gene ID: 12505 |
Catalog # | ABIN133979 |
Price | $284 |
Order / More Info | CD44 Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |