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Antigenic Specificity | ATAD5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 100 µg |
Concentration | 0.50 mg/mL |
Applications | ELISA, Western Blotting |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ELG1 (also known as ATP(GTP)-binding protein or Chromosome fragility associated gene 1) is involved in a novel RFC complex that is probably involved in DNA damage and repair by ensuring replication fidelity. This antibody detects a band at about 120kDa in Hela, A431, Jurkat and HEK193 cells. This corresponds to the band size seen in Kanellis P et al. It remains unclear why the band size detected is much less than the 207kDa predicted in the protein sequence corresponding to CACC44537.2 (Q96QE3), but as our results correspond to those seen in Kanellis P et al. it is likely that the 120 kDa target is ELG1.Target Information: Involved in DNA damage response. Involved in a RAD9A- related damage checkpoint, a pathway that is important in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. Modulates the RAD9A interaction with BCL2 and thereby induces DNA damages- induced apoptosis. |
Immunogen | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 63-76 of Human Elg 1. |
Other Names | C17orf41|ELG1|FRAG1|ATPase family AAA domain-containing protein 5|chromosome fragility associated gene 1|chromosome fragility-associated gene 1 protein|enhanced level of genomic instability 1 homolog|ATPase family, AAA domain containing 5|ATAD5|C130052G03Rik|Gm17|RGD1561464|enhanced level of genomic instability gene 1|ATPase family|AAA domain containing 5|Si:ch211-11k18.10 protein-like|cb14|im:7138471|sb:cb14|si:ch211-11k18.10|wu:fi03a11|ATPase family, AAA domain containing 5a|atad5a|ATPase family AAA domain-containing protein 5-like |
Gene, Accession # | Gene ID: 79915 |
Catalog # | ABIN129617 |
Price | $537 |
Order / More Info | ATAD5 Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |