VWF Antibody from ANTIBODIES-ONLINE GmbH

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Antigenic SpecificityVWF
CloneVWF-1767
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b kappa
Formatunconjugated
Size100 µg
Concentration200 µg/mL
ApplicationsCoating, ELISA, Immunohistochemistry, Staining Methods
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Descriptionvon Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi's sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen. Target Information: The glycoprotein encoded by this gene functions as both an antihemophilic factor carrier and a platelet-vessel wall mediator in the blood coagulation system. It is crucial to the hemostasis process. Mutations in this gene or deficiencies in this protein result in von Willebrand's disease. An unprocessed pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008].
ImmunogenRecombinant fragment (around aa1815-1939) of human vWF protein (exact sequence is proprietary)
Other Namessi:ch1073-474e24.1|von Willebrand factor|vwf|F8VWF|VWD|coagulation factor VIII VWF|6820430P06Rik|AI551257|B130011O06Rik|C630030D09
Gene, Accession #Gene ID: 7450
Catalog #ABIN6940897
Price$575
Order / More InfoVWF Antibody from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
Schloss-Rahe-Str. 15
52072 Aachen GERMANY
P: +49 (0)241 95 163 153
F: +49 (0)241 95 163 155

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