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Antigenic Specificity | DAXX |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 100 µg |
Concentration | 1.06 mg/mL |
Applications | ELISA, Western Blotting |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. DAXX, the Death domain-associated protein 6 (also named Fas death domain-associated protein, ETS1-associated protein 1Target Information: This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]. |
Immunogen | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 261-274 of human DAXX protein. |
Other Names | BING2|DAP6|EAP1|CENP-C binding protein|ETS1-associated protein 1|Fas-binding protein|death domain-associated protein 6|death-associated protein 6|fas death domain-associated protein|death domain associated protein|DAXX|Death-Domain Associated Protein|LOC100226911|death associated protein 3|28S ribosomal protein S29, mitochondrial|LOW QUALITY PROTEIN: death domain-associated protein 6|death-associated protein 6 L homeolog|daxx.L|si:dz179b20.7|wu:fd15c03|fas-binding |
Gene, Accession # | Gene ID: 1616 |
Catalog # | ABIN129710 |
Price | $537 |
Order / More Info | DAXX Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |