Selectin E/CD62e Antibody from ANTIBODIES-ONLINE GmbH

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Antigenic SpecificitySelectin E/CD62e
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatunconjugated
Size50 µg
Concentrationn/a
ApplicationsImmunoassay, Immunostaining, Western Blotting
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DescriptionThe antibody reacts with the Lectin Domain of E-selectin, CD62-e, formerly designated Endothelial Leucocyte Adhesion Molecule-1 (ELAM-1). The antibody reacts with human endothelial cells activated with TNF, IL-1 or endotoxin. The antibody was found to react also with cells transfected with the ELAM-1 gene. The antibody inhibits the adhesion of granulocytes both neutrophilic and eosinophilic. Target Information: The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq, Jul 2008].
Immunogenn/a
Other NamesCD62E|ELAM|ELAM1|ESEL|LECAM2|CD62 antigen-like family member E|E-selectin|ELAM-1|endothelial adhesion molecule 1|endothelial leukocyte adhesion molecule 1|leukocyte endothelial cell adhesion molecule 2|leukocyte-endothelial cell adhesion molecule 2|selectin E|SELE|Selectin E/CD62e|selectin E (endothelial adhesion molecule 1)|selectin|endothelial cell|E-selectin-like|selectin, endothelial cell|si:ch211-260g14.8|uncharacterized protein LOC558139
Gene, Accession #Gene ID: 6401
Catalog #ABIN2192183
Price$561
Order / More InfoSelectin E/CD62e Antibody from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
Schloss-Rahe-Str. 15
52072 Aachen GERMANY
P: +49 (0)241 95 163 153
F: +49 (0)241 95 163 155

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