Dendritic Cells Antibody from ANTIBODIES-ONLINE GmbH

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Antigenic SpecificityDendritic Cells
CloneOX-62
Host SpeciesMouse
Reactive Speciesrat
IsotypeIgG1
Formatfluorescein (FITC) conjugate
Size100 µg
Concentration0.1 mg/ml
ApplicationsFlow Cytometry
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DescriptionABIN133165 (OX-62) monoclonal antibody was raised against density gradient-enriched rat veiled (dendritic) cells obtained from lymph. This antibody only labeled cells characteristic of veiled cells the antigen recognized by ABIN133165 is expressed at low to moderate levels by a subset of spleen, thymus and bone marrow dendritic cells. In lymphoid tissues, the labeling correlated with dendritic cells (DC), however in skin, MHC Class II cells were ABIN133165 , while other CD3 cells with dendritic morphology were strongly stained with ABIN133165. Therefore, it seems that this antibody may be restricted to DC and probably T cells. (This has since been contradicted by the fact that the CD3 cells with dendritic morphology were confirmed to stain negative for ABIN133204 (OX-19), and are therefore not T cells.) The ABIN133165 antigen has the biochemical characteristics of an integrin (ABIN133165 recognizes the -like subunit) as determined by SDS-PAGE. This monoclonal antibody is useful for cell purification, delineating lineage relationships among cells with dendritic morphology and for molecular studies. The OX-62 antigen is not essential for T cell activation. The ABIN133165 clone has been use in flow cytometry, immunohistochemistry, immunoprecipitation and cell surface radioiodination.
Immunogenn/a
Other Namesn/a
Gene, Accession #n/a
Catalog #ABIN133418
Price$280
Order / More InfoDendritic Cells Antibody from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
Schloss-Rahe-Str. 15
52072 Aachen GERMANY
P: +49 (0)241 95 163 153
F: +49 (0)241 95 163 155

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