ITGA3 Antibody from ANTIBODIES-ONLINE GmbH

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Antigenic SpecificityITGA3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatunconjugated
Size120 µL
Concentration1.32 mg/mL
ApplicationsELISA, Immunohistochemistry
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DescriptionITGA3,also named as MSK18,CD49c,GAPB3 and FRP-2,belongs to the integrin alpha chain family. It is a receptor for fibronectin,laminin,collagen,epiligrin,thrombospondin and CSPG4. ITGA3 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. ITGA3 is highly concentrated in epithelial cells where it strongly adheres to Laminin-5 and Laminin-5 induced rapid adhesion can be blocked by antibodies against the alpha-3 integrin subunit. It can be cleaved into heavy chain(840aa) and light chain(176aa). This antibody can recognize the heavy chain. Target Information: The protein encoded by this gene belongs to the family of integrins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain, and function as cell surface adhesion molecules. This gene encodes alpha 3 subunit, which undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 subunit to form an integrin that interacts with many extracellular-matrix proteins. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008].
ImmunogenSynthetic peptide of human ITGA3
Other NamesCD49C|GAP-B3|GAPB3|ILNEB|MSK18|VCA-2|VL3A|VLA3a|CD49 antigen-like family member C|FRP-2|VLA-3 subunit alpha|antigen identified by monoclonal antibody J143|galactoprotein B3|integrin alpha-3|very late activation protein 3 receptor|alpha-3 subunit|integrin subunit alpha 3|ITGA3|Integrin, alpha 3 (Antigen CD49C, alpha 3 Subunit of VLA-3 Receptor)|integrin alpha 3 subunit|integrin|alpha 3 (antigen CD49C|alpha 3 subunit of VLA-3 receptor)|integrin subunit alpha 3 S homeolog|itga3.S|integrin alpha 3|integrin alpha-3-like|AA407068|VLA-3 alpha 3|VLA-3 receptor|alpha 3 subunit|alpha3-integrin
Gene, Accession #Gene ID: 3675, 16400
Catalog #ABIN7245319
Price$319
Order / More InfoITGA3 Antibody from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
Schloss-Rahe-Str. 15
52072 Aachen GERMANY
P: +49 (0)241 95 163 153
F: +49 (0)241 95 163 155

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