CD43 Antibody from ANTIBODIES-ONLINE GmbH
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| Antigenic Specificity | CD43 |
| Clone | W3-13HLK |
| Host Species | Mouse |
| Reactive Species | rat |
| Isotype | IgG1 |
| Format | biotin conjugate |
| Size | 100 µg |
| Concentration | 0.1 mg/ml |
| Applications | Flow Cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | anti-rat CD43 monoclonal antibody recognizes a monomorphic determinant expressed on rat thymocytes, polymorphonuclear cells, plasma cells and stem cells, but not B lymphocytes or pre-B cells (1,3). The antigen is a heavily glycosylated glycoprotein of apparent molecular weight 95 kDa and has a high content of O-linked carbohydrate structures (3). This major glycoprotein of thymocytes and T lymphocytes is referred to by several names including leukocyte sialoglycoprotein and leukosialin. The carbohydrate structures of leukosialin account for approximately 60% of its weight (2). On thymocytes, this glycoprotein is the main target for binding of peanut lectin (4). This antibody is useful for labelling T but not B lymphocytes and in studies on stem cells since pre-B cells are not labelled while the multipotential stem cell is. It may also be used in analysis of NK cells (5) and in molecular studies of the sialoglycoprotein which it recognizes. Target Information: The protein encoded by this gene is a major sialoglycoprotein found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It may be part of a physiologic ligand-receptor complex involved in T-cell activation. During T-cell activation, this protein is actively removed from the T-cell-APC (antigen-presenting cell) contact site, suggesting a negative regulatory role in adaptive immune response. [provided by RefSeq, Sep 2011]. |
| Immunogen | Rat thymocyte membrane . Fusion Partner: NS1/1 . Immunocyte Donor: BALB/c spleen |
| Other Names | CD43|GALGP|GPL115|LSN|galactoglycoprotein|leukocyte sialoglycoprotein|leukosialin|sialophorin (gpL115|CD43)|sialophorin|SPN|A630014B01Rik|Ly-48|Ly48|3E8 antigen|B-cell differentiation antigen LP-3|lymphocyte antigen 48|Lsn1|W313 antigen|leukosianin|sialophorin (leukosialin |
| Gene, Accession # | Gene ID: 24796 |
| Catalog # | ABIN133167 |
| Price | $280 |
| Order / More Info | CD43 Antibody from ANTIBODIES-ONLINE GmbH |
| Product Specific References | n/a |
ANTIBODIES-ONLINE GmbH
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