CD45RA Or A/B Antibody from ANTIBODIES-ONLINE GmbH
Search, find, compare suppliers for anti-CD45RA Or A/B antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | CD45RA Or A/B |
| Clone | OX-33 |
| Host Species | Mouse |
| Reactive Species | rat |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 250 µg |
| Concentration | 1.0 mg/ml |
| Applications | Flow Cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The rat CD45 antigen (Leukocyte Common Antigen (L-CA)) has been shown to exist in different forms on different lymphoid cell types. CD45 on thymocytes shows one main band at 180 kDa, T cells show 4 bands at 180, 190, 200 and 220 kDa. ABIN133310detects a subfraction of the 240 kDa rat CD45 band found only on B lymphocytes. This monoclonal antibody is of particular use in the investigation of the molecular and antigenic heterogeneity of rat L-CA, especially when used in conjunction with other OX antibodies. Four mouse monoclonal antibodies (MRC OX 1, 28, 29 and 30) react with all molecular forms of L-CA and fall into two sets that are non-competitive in binding to L-CA (MRC OX 1, 28, 29 and 30). The antigenic determinants seen by all these antibodies are lost when L-CA is reduced and alkylated. Three antibodies (MRC OX 22, 31, and 32) react selectively with B cells, T cytotoxic cells and about two thirds of T helper cells. OX 22 and OX 31 compete for binding but are non- competitive with OX 32. All of these antibodies bind to a sub-fraction of the 190, 200 and 220 kDa forms of T cell L-CA but not at all to the 180 kDa form of T cells or thymocytes. This clone works in flow cytometry and with frozen and paraffin sections (2). |
| Immunogen | Rat purified spleen L-CA . Fusion Partner: NSO/U . Donor: BALB/c spleen |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | ABIN133310 |
| Price | $288 |
| Order / More Info | CD45RA Or A/B Antibody from ANTIBODIES-ONLINE GmbH |
| Product Specific References | n/a |
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
Schloss-Rahe-Str. 15
52072 Aachen GERMANY
P: +49 (0)241 95 163 153
F: +49 (0)241 95 163 155
info@antibodies-online.com
Orders: orders@antibodies-online.com
Technical Support: support@antibodies-online.com
https://www.antibodies-online.com
Profile of ANTIBODIES-ONLINE GmbH
Return to Antibodies