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Antigenic Specificity | H-2Dd |
Clone | 34-2-12 |
Host Species | Mouse |
Reactive Species | mouse |
Isotype | IgG2a |
Format | fluorescein (FITC) conjugate |
Size | 0.5 mg |
Concentration | n/a |
Applications | Flow Cytometry, Immunofluorescence |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The 34-2-12 antibody (also known as 34-2-12S) recognizes the alpha3 domain of the H-2D^[d]. The binding of the antibody to its epitope is independent of the alpha1 and alpha2 domains and beta2 microglobulin. It cross-reacts with cells of the C3H.LG/Ckc strain. Reactivity with other haplotypes (eg, b, f, k, p, q, r, s) has not been observed. Soluble mAb 34-2-12 blocks binding of the Ly-49A-expressing T lymphoma EL4 to immobilized H-2D[d]. However, further studies utilizing this mAb indicate that the alpha3 domain is not involved in the interaction between Ly-49A, or Ly-49G2, and H-2D[d]. |
Immunogen | C57BL/6 x DBA/2)F1 mouse splenocytes |
Other Names | MHC Class I H-2Dd|H-2Dd |
Gene, Accession # | n/a |
Catalog # | ABIN1112495 |
Price | $505 |
Order / More Info | H-2Dd Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |