FAS Antibody from ANTIBODIES-ONLINE GmbH
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| Antigenic Specificity | FAS |
| Clone | R-125224 |
| Host Species | Human |
| Reactive Species | human |
| Isotype | IgG1 kappa |
| Format | unconjugated |
| Size | 200 µg |
| Concentration | n/a |
| Applications | Activation, BioImaging, ELISA, Flow Cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Human anti-FAS monoclonal antibody, unconjugated |
| Immunogen | R-125224 is generated by the humanization of the murine HFE7A anti-Fas antibody by grafting the CDR regions to the framework regions of the human 8E10 antibody and substituting key framework residues from the murine antibody into the 8E10 sequence. The original HFE7A was derived from a hybridoma cell line generated by the fusion of NS1 myeloma cells with splenocytes from Fas-deficient mice which had been immunized with partially purified recombinant human Fas-AIC2A chimera protein consisting of the extracellular region of human Fas antigen (aa -16 to 150) and the extracellular region of the murine IL-3 receptor AIC2 (aa 3-423). The HFE7A hybridoma was selected after screening by flow cytometry for the production of antibodies with the ability to bind to the WR19L12a transformed murine T cell lymphoma cell line expressing human Fas or the L5178YA1 cell line expressing murine Fas, but not to the parental WR19L or L5178Y cells. |
| Other Names | ALPS1A|APO-1|APT1|CD95|FAS1|FASTM|TNFRSF6|APO-1 cell surface antigen|CD95 antigen|Delta FasAPO-1CD95|FAS 827dupA|FASLG receptor|Fas (TNF receptor superfamily|member 6)|Fas AMA|TNF receptor superfamily member 6|apoptosis antigen 1|apoptosis-mediating surface antigen FAS|tumor necrosis factor receptor superfamily member 6|tumor necrosis factor receptor superfamily|member 6|Fas cell surface death receptor|FAS|TNF Receptor Superfamily, Member 6|FASL|TNFSF6|fas antigen ligand|tumor necrosis factor (ligand) superfamily|tumor necrosis factor ligand superfamily member 6|Fas ligand|FASLG|APO-1 ligand|CD95 ligand|TNF superfamily|Fas antigen|APT1LG1|CD178|CD95-L|CD95L|Fas-L|gld|generalized lymphoproliferative disease|Fas ligand (TNF superfamily, member 6)|14-3-3 protein zetadelta|KCIP-1|factor activating exoenzyme S|protein kinase C inhibitor protein 1|tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta|YWHAZ|AI196731|APO1|TNFR6|lpr|Fas (TNF receptor superfamily member)|apo-1 antigen|lymphoproliferation|Fas (TNF receptor superfamily member 6)|Fas antigen (ATP1)|Fas receptor|apoptosis (APO-1) antigen 1 ( FAS )|Fas receptor CD95 |
| Gene, Accession # | Gene ID: 355 |
| Catalog # | ABIN7072408 |
| Price | $522 |
| Order / More Info | FAS Antibody from ANTIBODIES-ONLINE GmbH |
| Product Specific References | n/a |
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
Schloss-Rahe-Str. 15
52072 Aachen GERMANY
P: +49 (0)241 95 163 153
F: +49 (0)241 95 163 155
info@antibodies-online.com
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