CD44 Antibody from ANTIBODIES-ONLINE GmbH

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Antigenic SpecificityCD44
CloneOX-49
Host SpeciesMouse
Reactive Speciesrat
IsotypeIgG2a
Formatbiotin conjugate
Size100 µg
Concentration0.1 mg/ml
ApplicationsFlow Cytometry, Immunohistochemistry (Frozen Sections), Immunohistochemistry (Paraffin-embedded Sections), Western Blotting
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Descriptionanti-rat CD44 (OX-49) monoclonal antibody recognizes rat CD44 (Pgp-1), also called CD44H. This antigen is expressed on most leukocytes (except a sub population of B cells) and increases upon activation. The OX-49 antibody binds extracellularly to the standard (S) form on rat leukocytes but it is not known if they bind to the N-terminal region. It has also been reported that the antibody may bind to melanoma cell lines that express CD44V (splice variant form). This antibody is suitable for flow cytometry, Western Blotting and immunohistochemisty on frozen and paraffin sections. Target Information: The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008].
ImmunogenT cell blasts . Fusion Partner: myeloma cell line NSO/1 . Donor: BALB/c spleen
Other NamesCDW44|CSPG8|ECMR-III|HCELL|HUTCH-I|IN|LHR|MC56|MDU2|MDU3|MIC4|Pgp1|CD44 antigen|GP90 lymphocyte homingadhesion receptor|Hermes antigen|cell surface glycoprotein CD44|chondroitin sulfate proteoglycan 8|epican|extracellular matrix receptor III|hematopoietic cell E- and L-selectin ligand|heparan sulfate proteoglycan|homing function and Indian blood group system|hyaluronate receptor|phagocytic glycoprotein 1|CD44 molecule (Indian blood group)|CD44|syndecan 4 (amphiglycan|ryudocan)|syndecan-4|syndecan 4|SDC4|AU023126|AW121933|AW146109|HERMES|Ly-24|Pgp-1|PGP-I|lymphocyte antigen 24|phagocytic glycoprotein I|CD44A|METAA|RHAMM|Cell surface glycoprotein CD44 (hyaluronate binding protein)|CD44-like protein|extracellular matrix receptor-III|lymphocyte surface antigen precursor CD44|XCD44|mutch-i|CD44 molecule (Indian blood group) S homeolog|hyaluronan receptor CD44|cd44.S
Gene, Accession #Gene ID: 25406
Catalog #ABIN133364
Price$280
Order / More InfoCD44 Antibody from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
Schloss-Rahe-Str. 15
52072 Aachen GERMANY
P: +49 (0)241 95 163 153
F: +49 (0)241 95 163 155

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