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Antigenic Specificity | CD109 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 60 µL |
Concentration | 1 mg/mL |
Applications | Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD109,also named as CPAMD7,is a member of the alpha2-macroglobulin/complement superfamily. It is a glycosylphosphatidylinositol (GPI)-linked cell surface glycoprotein of approximately 170kd which is found on the cell surface of platelets,activated T-cells,and endothelial cells. CD109 binds to and negatively regulates signaling of transforming growth factor beta (TGF-beta). CD109 has been identified as part of the TGF-beta receptor system in human keratinocytes. Up regulation of CD109 expression has been observed in several different types of tumor. Multiple transcript variants encoding different isoforms have been found for CD109. The antibody can recognize all these 4 isoforms. Target Information: This gene encodes a member of the alpha2-macroglobulin/complement superfamily. The encoded GPI-linked glycoprotein is found on the cell surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signaling of transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2009]. |
Immunogen | Recombinant Human CD109 antigen protein |
Other Names | CPAMD7|RP11-525G3.1|150 kDa TGF-beta-1-binding protein|C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7|CD109 antigen|Gov platelet alloantigens|activated T-cell marker CD109|p180|platelet-specific Gov antigen|r150|CD109 molecule|CD109|CD109 antigen-like|9930012E15Rik|AI480638|GARP|GPI-anchored alpha 2 macroglobulin-related protein|GPI-anchored alpha-2 macroglobulin-related protein |
Gene, Accession # | Gene ID: 2615, 235505, 363104 |
Catalog # | ABIN7234424 |
Price | $192 |
Order / More Info | CD109 Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |