CD109 Antibody from ANTIBODIES-ONLINE GmbH

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Antigenic SpecificityCD109
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatunconjugated
Size60 µL
Concentration1 mg/mL
ApplicationsImmunohistochemistry
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DescriptionCD109,also named as CPAMD7,is a member of the alpha2-macroglobulin/complement superfamily. It is a glycosylphosphatidylinositol (GPI)-linked cell surface glycoprotein of approximately 170kd which is found on the cell surface of platelets,activated T-cells,and endothelial cells. CD109 binds to and negatively regulates signaling of transforming growth factor beta (TGF-beta). CD109 has been identified as part of the TGF-beta receptor system in human keratinocytes. Up regulation of CD109 expression has been observed in several different types of tumor. Multiple transcript variants encoding different isoforms have been found for CD109. The antibody can recognize all these 4 isoforms. Target Information: This gene encodes a member of the alpha2-macroglobulin/complement superfamily. The encoded GPI-linked glycoprotein is found on the cell surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signaling of transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2009].
ImmunogenRecombinant Human CD109 antigen protein
Other NamesCPAMD7|RP11-525G3.1|150 kDa TGF-beta-1-binding protein|C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7|CD109 antigen|Gov platelet alloantigens|activated T-cell marker CD109|p180|platelet-specific Gov antigen|r150|CD109 molecule|CD109|CD109 antigen-like|9930012E15Rik|AI480638|GARP|GPI-anchored alpha 2 macroglobulin-related protein|GPI-anchored alpha-2 macroglobulin-related protein
Gene, Accession #Gene ID: 2615, 235505, 363104
Catalog #ABIN7234424
Price$192
Order / More InfoCD109 Antibody from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
Schloss-Rahe-Str. 15
52072 Aachen GERMANY
P: +49 (0)241 95 163 153
F: +49 (0)241 95 163 155

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