CD45RB Antibody from ANTIBODIES-ONLINE GmbH

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Antigenic SpecificityCD45RB
CloneMC5-2
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatallophycocyanin (APC) conjugate
Size100 tests
Concentrationn/a
ApplicationsFlow Cytometry, Immunofluorescence
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DescriptionThe antibody reacts with the LCA complex expressed on all haemopoietic cells but not platelets (190, 205, 200 kDa). Target Information: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012].
Immunogenn/a
Other NamesB220|CD45|CD45R|GP180|L-CA|LCA|LY5|T200|CD45 antigen|T200 glycoprotein|T200 leukocyte common antigen|protein tyrosine phosphatase|receptor type|c polypeptide|receptor-type tyrosine-protein phosphatase C|protein tyrosine phosphatase, receptor type C|PTPRC|CD45RB|Ly-5|Lyt-4|loc|leukocyte common antigen|lymphocyte antigen 5|lymphocyte common antigen|protein tyrosine phosphatase, receptor type, C
Gene, Accession #Gene ID: 5788
Catalog #ABIN1112162
Price$404
Order / More InfoCD45RB Antibody from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
Schloss-Rahe-Str. 15
52072 Aachen GERMANY
P: +49 (0)241 95 163 153
F: +49 (0)241 95 163 155

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