Edit |   |
---|---|
Antigenic Specificity | CD45RB |
Clone | MC5-2 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | allophycocyanin (APC) conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | Flow Cytometry, Immunofluorescence |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody reacts with the LCA complex expressed on all haemopoietic cells but not platelets (190, 205, 200 kDa). Target Information: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]. |
Immunogen | n/a |
Other Names | B220|CD45|CD45R|GP180|L-CA|LCA|LY5|T200|CD45 antigen|T200 glycoprotein|T200 leukocyte common antigen|protein tyrosine phosphatase|receptor type|c polypeptide|receptor-type tyrosine-protein phosphatase C|protein tyrosine phosphatase, receptor type C|PTPRC|CD45RB|Ly-5|Lyt-4|loc|leukocyte common antigen|lymphocyte antigen 5|lymphocyte common antigen|protein tyrosine phosphatase, receptor type, C |
Gene, Accession # | Gene ID: 5788 |
Catalog # | ABIN1112162 |
Price | $404 |
Order / More Info | CD45RB Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |