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Antigenic Specificity | RT1-BB |
Clone | OX-6 |
Host Species | Mouse |
Reactive Species | mouse, rat |
Isotype | IgG1 |
Format | unconjugated |
Size | 250 µg |
Concentration | 0,388888889 |
Applications | Flow Cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | anti-rat RT1.B monoclonal antibody recognizes Ia from all rat strains tested. It labels a monomorphic determinant of the rat Ia antigen present on the majority of peripheral B lymphocytes, dendritic cells, some macrophages, and certain epithelial cells (2,3,4) but not peripheral T lymphocytes. (4) This antibody also cross reacts with murine Ia antigens (particularly with k and s haplotypes). Analysis of recombinant strains shows that the determinant maps to the I-A region of the mouse MHC (1,2) and correlates with mouse Ia specificity 17 or 18. Thus, the determinant recognized by ABIN133234is polymorphic in the mouse. This antibody may be useful for recognizing the rat Ia antigen and can be coupled to Sepharose 4B for purification of rat Ia antigen by antibody affinity chromatography (1). This clone is reported to work with frozen and paraffin sections (5). Target Information: may play a role in antigen presentation [RGD, Feb 2006]. |
Immunogen | Rat thymocyte membrane glycoprotein. . FUSION PARTNER: P3-NS1-1-Ag4 (NS1/1) . IMMUNOCYTE DONOR: BALB/c spleen |
Other Names | RT1.B|MHC class II antigen B beta chain|RT1 class II histocompatibility antigen|B-1 beta chain|RT1.B-beta(1)|RT1.Bbeta 1|rano class II histocompatibility antigen|RT1 class II, locus Bb|RT1-Bb |
Gene, Accession # | Gene ID: 309622 |
Catalog # | ABIN133234 |
Price | $288 |
Order / More Info | RT1-BB Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |