RT1-BB Antibody from ANTIBODIES-ONLINE GmbH

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Antigenic SpecificityRT1-BB
CloneOX-6
Host SpeciesMouse
Reactive Speciesmouse, rat
IsotypeIgG1
Formatunconjugated
Size250 µg
Concentration0,388888889
ApplicationsFlow Cytometry
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Descriptionanti-rat RT1.B monoclonal antibody recognizes Ia from all rat strains tested. It labels a monomorphic determinant of the rat Ia antigen present on the majority of peripheral B lymphocytes, dendritic cells, some macrophages, and certain epithelial cells (2,3,4) but not peripheral T lymphocytes. (4) This antibody also cross reacts with murine Ia antigens (particularly with k and s haplotypes). Analysis of recombinant strains shows that the determinant maps to the I-A region of the mouse MHC (1,2) and correlates with mouse Ia specificity 17 or 18. Thus, the determinant recognized by ABIN133234is polymorphic in the mouse. This antibody may be useful for recognizing the rat Ia antigen and can be coupled to Sepharose 4B for purification of rat Ia antigen by antibody affinity chromatography (1). This clone is reported to work with frozen and paraffin sections (5). Target Information: may play a role in antigen presentation [RGD, Feb 2006].
ImmunogenRat thymocyte membrane glycoprotein. . FUSION PARTNER: P3-NS1-1-Ag4 (NS1/1) . IMMUNOCYTE DONOR: BALB/c spleen
Other NamesRT1.B|MHC class II antigen B beta chain|RT1 class II histocompatibility antigen|B-1 beta chain|RT1.B-beta(1)|RT1.Bbeta 1|rano class II histocompatibility antigen|RT1 class II, locus Bb|RT1-Bb
Gene, Accession #Gene ID: 309622
Catalog #ABIN133234
Price$288
Order / More InfoRT1-BB Antibody from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
Schloss-Rahe-Str. 15
52072 Aachen GERMANY
P: +49 (0)241 95 163 153
F: +49 (0)241 95 163 155

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