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Antigenic Specificity | COX IV |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 120 µL |
Concentration | 0.82 mg/mL |
Applications | Immunofluorescence, Immunohistochemistry, Western Blotting |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | COX4I1,also named as COX4 and COXIV-1,belongs to the cytochrome c oxidase IV family. It is one of the nuclear-coded polypeptide chains of cytochrome c oxidase,the terminal oxidase in mitochondrial electron transport. COX4I1 is a marker for mitochondria. It has two isoforms (isoform 1 and 2). Isoform 1(COX4I1) is ubiquitously expressed and isoform 2 is highly expressed in lung tissues. COX4I1 is commonly used as a loading control. This antibody is specific to COX4I1 and do not cross reacts with COX4I2. Target Information: Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes isoform 2 of subunit IV. Isoform 1 of subunit IV is encoded by a different gene, however, the two genes show a similar structural organization. Subunit IV is the largest nuclear encoded subunit which plays a pivotal role in COX regulation. [provided by RefSeq, Jul 2008]. |
Immunogen | Recombinant protein corresponding to Mouse COX IV |
Other Names | COX4|COX4-1|COXIV|COX IV-1|cytochrome c oxidase polypeptide IV|cytochrome c oxidase subunit 4 isoform 1|mitochondrial|cytochrome c oxidase subunit 4I1|COX4I1|Cytochrome C Oxidase Subunit IV Isoform 1|COX IV|mg:bb02d03|zgc:110058|GB20012|cytochrome c oxidase subunit 4 isoform 1, mitochondrial|LOC412396|OXPHOS complex IV subunit IV|LOC780848|BMEII0322|RSal33209_1582|cytochrome c oxidase subunit IV|SJAG_00976|HMPREF0733_11926|AL024441|Cox4a|cytochrome c oxidase|subunit IVa|subunit 4a|subunit IV|cytochrome c oxydase subunit 4|cytochrome c oxidase IV subunit|cytochrome c oxidase subunit IV isoform 1 S homeolog|cox4i1.S|BcDNA:AT07685|CG10396|CX41|CX42|DmelCG10396|IV|CG10396 gene product from transcript CG10396-RB|CG10396-PA|CG10396-PB|COX4L-PA|COX4L-PB|cytochrome c oxidase subunit 4-like|COX4L |
Gene, Accession # | Gene ID: 1327, 12857, 29445 |
Catalog # | ABIN7249535 |
Price | $362 |
Order / More Info | COX IV Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |