Edit |   |
---|---|
Antigenic Specificity | STAT1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | unconjugated |
Size | 100 µg |
Concentration | 2.3 mg/mL |
Applications | ELISA, Western Blotting |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. Signal transducer and activator of transcription 1 (Stat1) belongs to a family of cytoplasmic transcription factors that can be activated (phosphorylated) by a cell surface receptor. Phosphorylation of Stat1 at Tyr701 induces Stat1 dimerization, nuclear translocation and DNA binding. Stat1 has two isoforms,Target Information: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]. |
Immunogen | This Protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to residues surrounding Y701 in the mouse STAT1 protein. |
Other Names | CANDF7|ISGF-3|STAT91|signal transducer and activator of transcription 1-alphaeta|signal transducer and activator of transcription-1|transcription factor ISGF-3 components p91p84|signal transducer and activator of transcription 1|STAT1|Signal Transducer and Activator of Transcription 1, 91kDa|2010005J02Rik|AA408197|XStat1|signal transducer and activator of transcription 1 L homeolog|stat1.L|STAT4|signal transducer and activator of transcription 4|transcription factor ISGF-3|DD6G4-4|STAT|dZ182H3.3|si:by134g18.2|si:by51f19.1|si:dz182h3.3|si:dz199m19.1|si:dz73o4.2|activator of transcription|signal transduction|LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-alphaeta|91kDa|signal transduction and activation of transcription 1|signal transduction and activation of transcription 1a|signal transducer and activator of transcription 1a|stat1a |
Gene, Accession # | Gene ID: 20846 |
Catalog # | ABIN233804 |
Price | $537 |
Order / More Info | STAT1 Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |