Edit |   |
---|---|
Antigenic Specificity | Complement C4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 1 mL |
Concentration | n/a |
Applications | Immunoelectrophoresis |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-Complement C4 polyclonal antibody, unconjugated |
Immunogen | C4 and C2 represent substrates for activated C1. Both components are present in serum in an inert form. C4 is composed of 3 polypeptide chains of three different types, alpha, beta, gamma . One of the chains is cleaved by the action of activated C1, resulting in activation of C4 exposing an binding site for the next component in the sequence, C2. C4 has a molecular weight of 205.000 and is present in plasma in an average concentration of 600 µ g/ml. The activation of C4 yields two peptide fragments: C4a (MW 8,000) and C4b (MW 198,000). This process shows a considerable degree of similarity to the activation of the components C3 and C5. The C4 is isolated as a homogenous protein for use in antiserum production. Freund's complete adjuvant is used in the first step of the immunization procedure. |
Other Names | C4B1|C4B12|C4B2|C4B3|C4B5|C4BD|C4B_2|C4F|CH|CO4|CPAMD3|C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3|Chido form of C4|basic complement C4|complement C4-B|complement C4B1a|complement C4B (Chido blood group)|C4B|Complement 4|C4|Complement C4|C4A2|C4A3|C4A4|C4A6|C4AD|C4S|CPAMD2|RG|C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2|C4A anaphylatoxin|Rodgers form of C4|acidic C4|acidic complement C4|complement C4-A|complement C4A (Rodgers blood group)|C4A|C4-1|complement component 4 (within H-2S)|complement component 4|gene 1|complement component 4B (Chido blood group)|complement component 4B (Childo blood group)|complement component 4A (Rodgers blood group)|C4-2|MHC-linked complement C4|complement component 4A|Slp|sex-limited protein|Ss |
Gene, Accession # | Gene ID: 721, 720 |
Catalog # | ABIN458098 |
Price | $284 |
Order / More Info | Complement C4 Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |