MYB Antibody from ANTIBODIES-ONLINE GmbH
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| Antigenic Specificity | MYB |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | unconjugated |
| Size | 100 µg |
| Concentration | 0.91 mg/mL |
| Applications | ELISA, Western Blotting |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. The transcription factor c-Myb plays an important role in the development of all hematopoietic lineages during definitive hematopoiesis. Its critical role in hematopoiesis has been first demonstrated in experiments with targeted disruption of the c-Myb gene where deletion of both alleles of the c-Myb gene was embryonally lethal due to severe anemia. c-Myb is a short-lived sequence specific DNA-binding protein that regulates transcription of several important genes involved directly in cellular processes such as proliferation, differentiation, and apoptosis. Post-translational modifications such as phosphorylation, acetylation, ubiquitination, and conjugation of SUMO proteins are crucial for modulation of the transactivation activity of c-Myb. Several phosphorylation sites serve to regulate c-Myb activity.Target Information: This gene encodes a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2009]. |
| Immunogen | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of mouse c-Myb protein surrounding amino acid residue 486. Immunogen Type: Peptide |
| Other Names | Cmyb|c-myb|c-myb_CDS|efg|c-myb protein (140 AA)|c-myb10A_CDS|c-myb13A_CDS|c-myb14A_CDS|c-myb8B_CDS|proto-oncogene c-Myb|transcriptional activator Myb|MYB proto-oncogene, transcription factor|MYB|V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)|AI550390|M16449|gag-myb protein|myb proto-oncogene protein|myeloblastosis proto-oncogene product|tumor-specific myb protein|myeloblastosis oncogene|Avian myeloblastosis viral (v-myb) oncogene homolog|transcriptional activator Myb-like|xmyb|DNA-binding transcriptional regulator|MYB proto-oncogene, transcription factor S homeolog|myb.S|c-myb proto-oncogene|transcription factor cmyb|v-myb avian myeloblastosis viral oncogene homolog|v-myb myeloblastosis viral oncogene homolog |
| Gene, Accession # | Gene ID: 17863 |
| Catalog # | ABIN964595 |
| Price | $537 |
| Order / More Info | MYB Antibody from ANTIBODIES-ONLINE GmbH |
| Product Specific References | n/a |
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
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