IFITM3 Antibody from ANTIBODIES-ONLINE GmbH
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| Antigenic Specificity | IFITM3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | unconjugated |
| Size | 120 µL |
| Concentration | 1 mg/mL |
| Applications | Immunofluorescence, Immunohistochemistry, Western Blotting |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | IFITM3,also named as interferon-inducible protein 1-8U,belongs to the CD225 family. It is IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens,namely influenza A H1N1 virus,West Nile virus (WNV),and dengue virus,by inhibiting the early steps of replication. IFITM3 is identified as interferon-induced cellular proteins that restrict infections by retroviruses and filoviruses and of influenza virus and flaviviruses,respectively. IFITM3,the most potent antiviral IFITM,was found to inhibit an uncharacterized early infectious event after VSV endocytosis,but before primary transcription of its viral genome. IFITM proteins are viral restriction factors that can inhibit infection mediated by the influenza A virus (IAV) hemagglutinin (HA) protein. They differentially restrict the entry of a broad range of enveloped viruses,and modulate cellular tropism independently of viral receptor expression. This antibody recognizes both IFITM2 and IFITM3. Target Information: The protein encoded by this gene is an interferon-induced membrane protein that helps confer immunity to influenza A H1N1 virus, West Nile virus, and dengue virus. Two transcript variants, only one of them protein-coding, have been found for this gene. Another variant encoding an N-terminally truncated isoform has been reported, but the full-length nature of this variant has not been determined. [provided by RefSeq, May 2012]. |
| Immunogen | Recombinant Rat Interferon-induced transmembrane protein 3 protein |
| Other Names | 1-8U|DSPA2b|IP15|dispanin subfamily A member 2b|interferon-induced transmembrane protein 3|interferon-inducible protein 1-8U|interferon induced transmembrane protein 3|IFITM3|rat8|interferon-inducible protein variant 10|ifm3|1110004C05Rik|Cd225|Cdw217|Fgls|mil-1|fragilis protein|ifitm-like protein 1|interferon-inducible protein 15|IFITM2|interferon-induced transmembrane protein 2|interferon-induced transmembrane protein 1-like|interferon-inducible transmembrane protein 3|interferon induced transmembrane protein family member|interferon induced transmembrane protein 3 L homeolog|ifitm3.L |
| Gene, Accession # | Gene ID: 10410, 66141, 361673 |
| Catalog # | ABIN7234050 |
| Price | $308 |
| Order / More Info | IFITM3 Antibody from ANTIBODIES-ONLINE GmbH |
| Product Specific References | n/a |
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
Schloss-Rahe-Str. 15
52072 Aachen GERMANY
P: +49 (0)241 95 163 153
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