SPTBN2 Antibody from ANTIBODIES-ONLINE GmbH
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| Antigenic Specificity | SPTBN2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | unconjugated |
| Size | 100 µL |
| Concentration | n/a |
| Applications | Immunofluorescence, Immunohistochemistry, Western Blotting |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | SPTBN2, also named as KIAA0302, belongs to the spectrin family. It probably plays an important role in neuronal membrane skeleton. Defects in SPTBN2 are the cause of spinocerebellar ataxia type 5 (SCA5). The antibody is specific to SPTBN2. Target Information: Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. [provided by RefSeq, Dec 2009]. |
| Immunogen | Recombinant protein corresponding to Mouse SPTBN2 |
| Other Names | GTRAP41|SCA5|beta-III spectrin|glutamate transporter EAAT4-associated protein 41|spectrin beta chain|brain 2|non-erythrocytic 2|spectrin|non-erythroid beta chain 2|spinocerebellar ataxia 5 protein|spectrin beta, non-erythrocytic 2|SPTBN2|Spectrin, Beta, Non-erythrocytic 2|Spnb3|mKIAA0302|beta-spectrin 3|spectrin beta 3|SPNB-3|beta SpIII sigma 1|spectrin-like protein GTRAP41 |
| Gene, Accession # | Gene ID: 6712, 20743, 29211 |
| Catalog # | ABIN7075698 |
| Price | $286 |
| Order / More Info | SPTBN2 Antibody from ANTIBODIES-ONLINE GmbH |
| Product Specific References | n/a |
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