CD3 Antibody from ANTIBODIES-ONLINE GmbH
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| Edit | |
|---|---|
| Antigenic Specificity | CD3 |
| Clone | SK7 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 kappa |
| Format | violetFluor™ 450 conjugate |
| Size | 100 tests |
| Concentration | n/a |
| Applications | Flow Cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The SK7 antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor - CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing cell proliferation, differentiation, production of cytokines or activation- induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.The SK7 antibody is a widely used phenotypic marker for human T cells. This antibody may induce T cell activation in the presence of monocytes. The antibody has also been demonstrated to be cross-reactive with Chimpanzee CD3. Binding of clone SK7 can be blocked by an alternative Anti-Human CD3 clone, OKT3. Please choose the appropriate format for each application. Target Information: The CD3 complex mediates signal transduction (By similarity). |
| Immunogen | n/a |
| Other Names | CD3|CD3 epsilon subunit|T-cell surface glycoprotein CD3 epsilon chain|CD3e molecule|CD3E|CD3 glycoprotein|CD3 type I transmembrane glycoprotein|CD3D antigen delta|CD3D antigen|delta polypeptide (TiT3 complex)|T-cell surface glycoprotein CD3 delta chain|T-cell surface protein|CD3d molecule|CD3D|AI504783|CD3epsilon|T3e|T-cell surface antigen T3Leu-4 epsilon chain|CD3 antigen, epsilon polypeptide|cd3-gamma|cd3g|cd3g-a|cd3gd|cd3gd|t3g|CD3 molecule|gammadelta (CD3-TCR complex)|CD3g molecule S homeolog|CD3g molecule|gamma (CD3-TCR complex)|CD3gammadelta|T-cell surface glycoprotein CD3 gammadelta chain homolog|cd3g.S |
| Gene, Accession # | Gene ID: 12501 |
| Catalog # | ABIN7278534 |
| Price | $281 |
| Order / More Info | CD3 Antibody from ANTIBODIES-ONLINE GmbH |
| Product Specific References | n/a |
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
Schloss-Rahe-Str. 15
52072 Aachen GERMANY
P: +49 (0)241 95 163 153
F: +49 (0)241 95 163 155
info@antibodies-online.com
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