CD177 Antibody from ANTIBODIES-ONLINE GmbH

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Antigenic SpecificityCD177
CloneMEM-166
Host SpeciesMouse
Reactive Specieshuman, non-human primate
IsotypeIgG1
Formatallophycocyanin (APC) conjugate
Size100 tests
Concentrationn/a
ApplicationsFlow Cytometry, Immunoprecipitation, Western Blotting
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DescriptionCD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN). Target Information: NB1, a glycosyl-phosphatidylinositol (GPI)-linked N-glycosylated cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia (Lalezari et al., 1971 [PubMed 5552408]).[supplied by OMIM, Mar 2008].
ImmunogenHuman granulocytes
Other NamesHNA-2a|HNA2A|NB1|NB1 GP|PRV-1|PRV1|CD177 antigen|NB1 glycoprotein|cell surface receptor|human neutrophil alloantigen 2a|polycythemia rubra vera 1|polycythemia rubra vera protein 1|CD177 molecule|CD177|RGD1562941|MGC157159|CD177 antigen-like|1190003K14Rik|Pdp3
Gene, Accession #Gene ID: 57126
Catalog #ABIN192245
Price$484
Order / More InfoCD177 Antibody from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
ANTIBODIES-ONLINE GmbH
Schloss-Rahe-Str. 15
52072 Aachen GERMANY
P: +49 (0)241 95 163 153
F: +49 (0)241 95 163 155

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