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Antigenic Specificity | CD177 |
Clone | MEM-166 |
Host Species | Mouse |
Reactive Species | human, non-human primate |
Isotype | IgG1 |
Format | allophycocyanin (APC) conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | Flow Cytometry, Immunoprecipitation, Western Blotting |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN). Target Information: NB1, a glycosyl-phosphatidylinositol (GPI)-linked N-glycosylated cell surface glycoprotein, was first described in a case of neonatal alloimmune neutropenia (Lalezari et al., 1971 [PubMed 5552408]).[supplied by OMIM, Mar 2008]. |
Immunogen | Human granulocytes |
Other Names | HNA-2a|HNA2A|NB1|NB1 GP|PRV-1|PRV1|CD177 antigen|NB1 glycoprotein|cell surface receptor|human neutrophil alloantigen 2a|polycythemia rubra vera 1|polycythemia rubra vera protein 1|CD177 molecule|CD177|RGD1562941|MGC157159|CD177 antigen-like|1190003K14Rik|Pdp3 |
Gene, Accession # | Gene ID: 57126 |
Catalog # | ABIN192245 |
Price | $484 |
Order / More Info | CD177 Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |