neurofilaments, primary sensory and motor neurons Antibody from DEVELOPMENTAL STUDIES HYBRIDOMA BANK

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Antigenic Specificityneurofilaments, primary sensory and motor neurons
CloneE1.9
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgM
FormatHYBRIDOMA
Size1 vial cells
Concentrationn/a
ApplicationsImmunofluorescence
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Descriptionfilaments in growing primary sensory and motor neurons. In the original paper for E1.9 [PMID: 2300585], the immunogen was described as rat E12, but the subsequent paper from the same authors and in the Depositor's notes it was described as mouse E11. The E1.9 epitope is developmentally regulated. E1.9 recognizes a cytoplasmic epitope in the primary sensory and motor neurons during axonal outgrowth, appearing at E8.5 and disappearing by E12 in the mouse when the same cell populations become positive for mAb B10. It stains neural crest-derived sensory neurons (e.g., neurons of dorsal root ganglia) as well as placode-derived sensory neurons (e.g.neurons of cranial nerves VII and VIII). It is not clear which filaments are recognized by this antibody. For this reason we didn't link it to a Uniprot or gene ID. See mAb B10 for a related antibody. Antibody Registry ID: AB_531876
ImmunogenWhole murine cells from the mid- and hindbrain (development stage: E12), Full length protein
Other Namesn/a
Gene, Accession #n/a
Catalog #E1.9
Priceplease inquire
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Product Specific ReferencesPubMed: 2300585
DEVELOPMENTAL STUDIES HYBRIDOMA BANK
DEVELOPMENTAL STUDIES HYBRIDOMA BANK
DEVELOPMENTAL STUDIES HYBRIDOMA BANK
Dr. David Soll
University of Iowa Dept. Biology
Iowa City IA 52242
P: 319-335-3826
F: 319-335-2077

dshb@uiowa.edu

http://dshb.biology.uiowa.edu

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