huntingtin (specific for expanded polyQ by western blot) Antibody from DEVELOPMENTAL STUDIES HYBRIDOMA BANK

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Antigenic Specificityhuntingtin (specific for expanded polyQ by western blot)
CloneMW1
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b, kappa
FormatHYBRIDOMA
Size1 vial cells
Concentrationn/a
ApplicationsELISA,FACS,Function Blocking,Immunofluorescence,Immunoprecipitation,Western Blot
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DescriptionEpitope: N-terminal, polyQ. MW1 is specific for the elongated polyQ stretch through which mHtt aggregates. The epitope is hidden in aggregates. This antibody is also known as anti-polyQ. Appears to recognize an altered conformation of the polyQ domain generated as the polyQ domain of Htt increases in length. Time-resolved Foerster resonance energy transfer (TR-FRET) assay has been developed using MW1 to assay soluble huntingtin. PMID: 22365609 23966247 23626768 23100324 22984513. RRID:AB_528290
ImmunogenRecombinant DRPLA-19Q/GST fusion protein, Partial protein
Other NamesHD, IT15
Gene, Accession #HTT, Gene ID: 3064, UniProt: P42858
Catalog #MW1
Priceplease inquire
Order / More Infohuntingtin (specific for expanded polyQ by western blot) Antibody from DEVELOPMENTAL STUDIES HYBRIDOMA BANK
Product Specific ReferencesPubMed: 11719267
DEVELOPMENTAL STUDIES HYBRIDOMA BANK
DEVELOPMENTAL STUDIES HYBRIDOMA BANK
DEVELOPMENTAL STUDIES HYBRIDOMA BANK
Dr. David Soll
University of Iowa Dept. Biology
Iowa City IA 52242
P: 319-335-3826
F: 319-335-2077

dshb@uiowa.edu

http://dshb.biology.uiowa.edu

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