MK-5435 from ALOMONE LABS
Search, find, compare suppliers for MK-5435 products.
| Edit | |
|---|---|
| Product Name | MK-5435 |
| Description | MK-5435 is a potent and selective allosteric mGluR1 antagonist, inhibiting human and rat mGluR1 with IC50 of 4.3 and 3.6 nM, respectively. It is selective over mGluR5 (IC50 = 1.5 µM), mGluR2 and mGluR8 (IC50 = 10 µM), and has no affinity for the quisqualic binding site (IC50 >10 µM). in vivo, following an oral dose of 1 mg/kg, plasma and brain concentrations in mice were 0.17 µM and 0.45 nmol/g respectively, at 30 min post-dose1. Synthetic. Purity >98%. MW: 368.39 |
| Size | 10 mg |
| Concentration | 10 nM - 10 µM. |
| Applications | n/a |
| Other Names | n/a |
| Gene, Accession, CAS # | n/a |
| Catalog # | M-265 |
| Price | please inquire |
| Order / More Info | MK-5435 from ALOMONE LABS |
| Product Specific References | n/a |
ALOMONE LABS
ALOMONE LABS
Jerusalem BioPark (JBP), Hadassah Ein Kerem
PO Box 4287
Jerusalem, 9104201 ISRAEL
P: +972-2-587-2202
F: +972-2-587-1101
info@alomone.com
http://www.alomone.com
U.S.A. OFFICE
Toll free phone: 1800-618-1644 / 1800-791-3904
Toll free fax: 1888-454-7276 / 1800-791-3912
Profile of ALOMONE LABS