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Product Name | Sitaxsentan |
Description | Sitaxsentan is a potent and selective antagonist of ET-A Endothelin receptors, inhibiting Endothelin-1 radioligand binding to human ET-A and ET-B receptors with IC50 of 1.4 nM and 9.8 µM, respectively (a 7000-fold selectivity). in vitro, Sitaxsentan inhibits Endothelin-1 induced phosphoinositide turnover with a pA2 of 8.01. Sitaxsentan is orally bioavailable and active in vivo1,2. Synthetic. Purity >99% (HPLC). MW: 454.9 |
Size | 10 mg |
Concentration | 1-100 nM. |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | CAS: 184036-34-8 |
Catalog # | S-186 |
Price | please inquire |
Order / More Info | Sitaxsentan from ALOMONE LABS |
Product Specific References | n/a |
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