Bosentan hydrate from ALOMONE LABS

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Product NameBosentan hydrate
DescriptionBosentan is a dual antagonist of the ET-A and ET-B endothelin receptors, shown to inhibit endothelin-1 radioligand binding to ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively. In vitro, it competitively inhibits aortic contractions induced by endothelin-1 and tracheal contractions induced by Sarafotoxin S6C with pA2 of 7.2 and 6.0, respectively1. Bosentan is orally bioavailable and active in vivo2. Synthetic. Purity >99% (HPLC). MW: 569.63
Size100 mg
Concentration0.1-100 nM.
Applicationsn/a
Other Namesn/a
Gene, Accession, CAS #CAS: 157212-55-0
Catalog #B-170
Priceplease inquire
Order / More InfoBosentan hydrate from ALOMONE LABS
Product Specific Referencesn/a
ALOMONE LABS
ALOMONE LABS
ALOMONE LABS
Jerusalem BioPark (JBP), Hadassah Ein Kerem
PO Box 4287
Jerusalem, 9104201 ISRAEL
P: +972-2-587-2202
F: +972-2-587-1101

info@alomone.com

http://www.alomone.com

U.S.A. OFFICE
Toll free phone: 1800-618-1644 / 1800-791-3904

Toll free fax: 1888-454-7276 / 1800-791-3912


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