Edit |   |
---|---|
Product Name | Bosentan hydrate |
Description | Bosentan is a dual antagonist of the ET-A and ET-B endothelin receptors, shown to inhibit endothelin-1 radioligand binding to ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively. In vitro, it competitively inhibits aortic contractions induced by endothelin-1 and tracheal contractions induced by Sarafotoxin S6C with pA2 of 7.2 and 6.0, respectively1. Bosentan is orally bioavailable and active in vivo2. Synthetic. Purity >99% (HPLC). MW: 569.63 |
Size | 100 mg |
Concentration | 0.1-100 nM. |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | CAS: 157212-55-0 |
Catalog # | B-170 |
Price | please inquire |
Order / More Info | Bosentan hydrate from ALOMONE LABS |
Product Specific References | n/a |
U.S.A. OFFICE
Toll free phone: 1800-618-1644 / 1800-791-3904
Toll free fax: 1888-454-7276 / 1800-791-3912