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Product Name | Isradipine |
Description | Isradipine is a dihydropyridine that acts as an L-type, voltage-gated Ca2+ channel blocker and is used in the clinic to treat hypertension1,2. Isradipine inhibits L-type channels expressed in Xenopus oocytes with IC50 = 0.2 µM at a holding potential of -80 mV and the inhibition is state dependent and increases with reduced membrane hyperpolarization2. Isradipine, was also shown recently to putatively be an effective treatment for Parkinson's disease, by affecting particularly the excitability of certain CaV1.3 expressing dopaminergic neurons3. Synthetic. Purity >99%. MW: 371.4 |
Size | 10 mg |
Concentration | 50 nM - 5 µM. |
Applications | n/a |
Other Names | DynaCirc®, Prescal® |
Gene, Accession, CAS # | CAS: 75695-93-1 |
Catalog # | I-100 |
Price | please inquire |
Order / More Info | Isradipine from ALOMONE LABS |
Product Specific References | n/a |
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