Isradipine from ALOMONE LABS

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Product NameIsradipine
DescriptionIsradipine is a dihydropyridine that acts as an L-type, voltage-gated Ca2+ channel blocker and is used in the clinic to treat hypertension1,2. Isradipine inhibits L-type channels expressed in Xenopus oocytes with IC50 = 0.2 µM at a holding potential of -80 mV and the inhibition is state dependent and increases with reduced membrane hyperpolarization2. Isradipine, was also shown recently to putatively be an effective treatment for Parkinson's disease, by affecting particularly the excitability of certain CaV1.3 expressing dopaminergic neurons3. Synthetic. Purity >99%. MW: 371.4
Size10 mg
Concentration50 nM - 5 µM.
Applicationsn/a
Other NamesDynaCirc®, Prescal®
Gene, Accession, CAS #CAS: 75695-93-1
Catalog #I-100
Priceplease inquire
Order / More InfoIsradipine from ALOMONE LABS
Product Specific Referencesn/a
ALOMONE LABS
ALOMONE LABS
ALOMONE LABS
Jerusalem BioPark (JBP), Hadassah Ein Kerem
PO Box 4287
Jerusalem, 9104201 ISRAEL
P: +972-2-587-2202
F: +972-2-587-1101

info@alomone.com

http://www.alomone.com

U.S.A. OFFICE
Toll free phone: 1800-618-1644 / 1800-791-3904

Toll free fax: 1888-454-7276 / 1800-791-3912


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