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Product Name | A-317491 sodium salt hydrate |
Description | A-317491 sodium salt hydrate is a selective antagonist of the P2X3 and P2X2/3 receptors. It was shown to inhibit human homomeric P2X3 and heteromeric P2X2/3 receptors with pIC50 values of ~7, whilst exhibiting little to no antagonistic activity on other P2X family receptors, and no effect on P2Y2 at over 10 µM1. This non-nucleotide antagonist reduces chronic inflammatory and neuropathic pain in the rat2. Synthetic. Purity >98% (HPLC). MW: 565.57 (free acid, anhydrous) |
Size | 10 mg |
Concentration | 50 nM - 50 µM. |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | CAS: 475205-49-3 |
Catalog # | A-380 |
Price | please inquire |
Order / More Info | A-317491 sodium salt hydrate from ALOMONE LABS |
Product Specific References | n/a |
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