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Product Name | CNQX disodium salt |
Description | AMPA/kainate receptor antagonist. The concentrations that inhibit 50% of AMPA binding (IC50) for CNQX in dorsal horn neurons and motoneurons are 300 nM-1.3 µM. It was about one-fifth as effective at kainate binding sites1,2. The association of AMPA receptors with TARPs converts CNQX from an antagonist to a weak partial agonist. CNQX binds with high affinity to both high and low affinity AMPA binding sites in rat brain. CNQX is a potent antagonist in electrophysiological responses mediated by non-NMDA receptors. Effects at NMDA receptors are much weaker. Synthetic. Purity >98%. MW: 276.1 |
Size | 1 mg |
Concentration | 300 nM - 500 µM. |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | CAS: 479347-85-8 |
Catalog # | C-141 |
Price | please inquire |
Order / More Info | CNQX disodium salt from ALOMONE LABS |
Product Specific References | n/a |
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