PhTx-74 from ALOMONE LABS

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Product NamePhTx-74
DescriptionPhTx-74 (Philanthotoxin-7,4) is a synthetic polyamine analogue of the naturally occurring wasp venom toxin philanthotoxin-4,3,3. It is a potent and selective antagonist of certain isoforms of the AMPA type of ionotropic glutamate receptors1. PhTx-74 inhibited GluR1 and GluR3 homomers as well as GluR1/GluR2 where 100 µM inhibited nearly 100% of the glutamate evoked currents. However, up to 500 µM had no or little effect on GluR2 or GluR2/GluR3 channels1-2. Synthetic. Purity >99% (HPLC). MW: 507.54
Size1 mg
Concentration0.1-100 µM.
Applicationsn/a
Other NamesPhilanthotoxin-7,4
Gene, Accession, CAS #CAS: 401601-12-5
Catalog #P-120
Priceplease inquire
Order / More InfoPhTx-74 from ALOMONE LABS
Product Specific Referencesn/a
ALOMONE LABS
ALOMONE LABS
ALOMONE LABS
Jerusalem BioPark (JBP), Hadassah Ein Kerem
PO Box 4287
Jerusalem, 9104201 ISRAEL
P: +972-2-587-2202
F: +972-2-587-1101

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