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Product Name | PhTx-74 |
Description | PhTx-74 (Philanthotoxin-7,4) is a synthetic polyamine analogue of the naturally occurring wasp venom toxin philanthotoxin-4,3,3. It is a potent and selective antagonist of certain isoforms of the AMPA type of ionotropic glutamate receptors1. PhTx-74 inhibited GluR1 and GluR3 homomers as well as GluR1/GluR2 where 100 µM inhibited nearly 100% of the glutamate evoked currents. However, up to 500 µM had no or little effect on GluR2 or GluR2/GluR3 channels1-2. Synthetic. Purity >99% (HPLC). MW: 507.54 |
Size | 1 mg |
Concentration | 0.1-100 µM. |
Applications | n/a |
Other Names | Philanthotoxin-7,4 |
Gene, Accession, CAS # | CAS: 401601-12-5 |
Catalog # | P-120 |
Price | please inquire |
Order / More Info | PhTx-74 from ALOMONE LABS |
Product Specific References | n/a |
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