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Product Name | ABCC5 ELISA Kit |
Description | Product Characteristics: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of ABCC5 in human tissue homogenates, cell lysates. Target Information: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing of this gene has been detected\, however, the complete sequence and translation initiation site is unclear. [provided by RefSeq, Jul 2008]. |
Size | 96 tests |
Concentration | n/a |
Applications | ELISA |
Other Names | ABC33|EST277145|MOAT-C|MOATC|MRP5|SMRP|pABC11|ATP-binding cassette sub-family C member 5|canalicular multispecific organic anion transporter C|multi-specific organic anion transporter C|multidrug resistance-associated protein 5|ATP binding cassette subfamily C member 5|ABCC5|ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 5|2900011L11Rik|AI132311|Abcc5a|Abcc5b|ATP-binding cassette|sub-family C (CFTR\/MRP)|member 5a|member 5b|sub-family C|member 5|ATP-binding cassette sub-family C (CFTR\/MRP) member 5a|ATP binding cassette subfamily C member 5 L homeolog|abcc5.L |
Gene, Accession, CAS # | Gene ID: 10057 |
Catalog # | ABIN6953382 |
Price | $773 |
Order / More Info | ABCC5 ELISA Kit from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |